Figure 1 | Scientific Reports

Figure 1

From: The ineluctable requirement for the trans-iron elements molybdenum and/or tungsten in the origin of life

Figure 1

(A) Structural superposition of the catalytic Molybdenum subunits from respiratory nitrate reductase (Nar, light and dark purple) and polysulfide reductase (Psr, blue and green). (B) Schematic sequence alignments between Nar and Psr. The second and third lines represent the alignment obtained fully automatically by ClustalX and T-Coffee whereas the bottom-line alignment is based on the structural information gathered from (A) and further processed as described above. In both (A) and (B), light purple stretches indicate parts of the Nar polypeptide chain for which no structural equivalents exist in Psr. The same applies for the light blue sequences stretches in Psr. The green stretches denote the part of the sequences for which Clustal- or T-Coffee- and structure-based alignments coincide.

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