Table 1 Enrichment analysis of the oncogenes or tumor suppressors of differentially expressed miRNAs in cancer treatment

From: Towards the understanding of microRNA and environmental factor interactions and their relationships to human diseases

Environmental factor

Cancer

Up-regulated miRNAs

Down-regulated miRNAs

Treatment Result

Reference PubMed ID

adriamycin

Leukemia

miRNA oncogene P = 9.21×10−3

miRNA tumor suppressor P = 8.90×10−5

Resistant

21122348

gemcitabine

Pancreatic Cancer

No miRNA data

miRNA tumor suppressor P = 6.86×10−8

Resistant

19654291

irradiation

Lung Cancer

miRNA tumor suppressor P = 2.69×10−3

miRNA oncogene P = 2.76×10−4

Sensitive

20728239

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