Figure 5
From: Metformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cells
Effect of metformin on the growth of spheres of MCF-7 and FSaII cells.
Cells were cultured for 8 days in ultralow attachment wells with sphere media containing different concentrations of metformin. (A) MCF-7 spheres grown with or without 0.1 mM metformin. (B) The numbers of sphere with > 50 µm in diameter obtained from 103 cells. Means of 5 experiments ± 1 S.E are shown. *P < 0.05 between control and metformin treated groups.
