Figure 1
From: TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
Potentiation of GLP-1 secretion by AERs is TGR5-dependent.
(a–f) Analysis of plasma from diet-induced obese TGR5+/+ and TGR5−/− mice after two weeks of treatment with Colestilan (COL; n = 7 per group). GLP-1 (a–b), insulin (c–d) and glucose (e–f) levels at indicated time points after test meal. Data represent mean ± SE. *Statistically significant, p<0.05, **p<0.01, ***p<0.001.
