Figure 3
From: TGR5 potentiates GLP-1 secretion in response to anionic exchange resins
TGR5-dependent GLP-1 secretion is induced by acute exposure of AERs.
(a–b) Plasma GLP-1 levels at indicated time points after test meal from high fat diet-induced obese TGR5+/+ mice (a) and TGR5−/− littermates (b) after three hours of treatment with Colestilan (COL; n = 7 per group). Data represent mean ± SE. *Statistically significant as compared to control group, p<0.05.
