Figure 1
From: Carcinogenicity evaluation for the application of carbon nanotubes as biomaterials in rasH2 mice
Survival rate and change in the weights of the transgenic rasH2 mice.
(a) Survival rate: All the mice in the CNT group and solvent group were alive at 26 weeks after injection. In the carbon black group, 1 mouse died at 22 weeks and the remaining 9 mice were alive at 26 weeks. In the MNU group, 1 mouse died at each of 12, 14, 17 and 21 weeks following the injection and the remaining 6 mice were alive at 26 weeks. The survival rate was statistically different between the MNU and CNT groups and between the MNU and control groups (p = 0.029406 for both comparisons). (b) Weight change in mice: The CNT group, carbon black group and solvent group showed similar weight change, while the 4 mice in MNU group that died before the end of the study period showed rapid decrease in weight from several weeks before death.
