Figure 2
From: Environmental conditioning in the control of macrophage thrombospondin-1 production
Effect of IFN-γ, IL-4 and IL-17 cytokines on BM-MΦ TSP-1 expression.
WT BM-MΦs were stimulated with LPS for 24 hrs followed by the addition of IFN-γ, IL-4, IL-17, or IFN-γ combined with IL-17 for a further 24 hrs. Cells stimulated with LPS alone for 48 hrs were used as controls. IFN-γ and IL-4 inhibited TSP-1 expression while IL-17 had no effect. Results are the averages from two independent experiments. Plots were gated on live F4/80+ cells. * p = <0.05 Mann-Whitney U test.
