Figure 3
From: Environmental conditioning in the control of macrophage thrombospondin-1 production
TSP-1 secretion is independent of the response of neighbouring cells.
WT and TSP-1 KO BM-MΦ's were cultured together at different ratios and stimulated with LPS for 48 hrs. Expression of TSP-1 by WT (CD45.1 positive) cells was independent of the proportion of TSP-1 KO cells present. Results are the averages for two independent experiments. TSP-1 gates are based on the positivity of TSP-1 KO cells being less than 1%.
