Figure 2
From: Predicting effects of structural stress in a genome-reduced model bacterial metabolism
Damage in cascades triggered by pairs of reactions.
(a–c). Cumulative probability distribution functions of damages in M. pneumoniae, E. coli and S. aureus. Results are compared with damages produced in randomized versions of the metabolic networks in order to discount structural effects. In each case, the solid black curve is the average over 100 realizations. Results of the Kolmogorov-Smirnov tests (K-S statistic/associated significance level): 0.15/0, 0.14/0 and 0.13/0 for M. pneumoniae, S. aureus and E. coli respectively. Taking α = 0.05, distributions of damages can be considered not consistent with those for randomized variants. (d) Most frequent double cascades output. Solid line: interference without amplification. It is related with cases b and c in Figure 3. Dashed line: no interference, which is related with case a in Figure 3. e) Non-linear effects in double cascades. Solid line: overlap. It is related with cases c and e in Figure 3. Dashed line: amplification. Amplification is related with cases d and e in Fig. 3.
