Figure 2
From: Importance of β-Catenin in glucose and energy homeostasis
Deletion of β-catenin in pancreatic progenitors results in impaired glucose metabolism.
Blood glucose levels measured after an overnight fast in Pdx1-Cre and Pβcat-KO at two (A) and five month of age (B) Intraperitoneal glucose tolerance tests were performed on Pdx1-Cre (black circles) and Pβcat-KO (grey squares) in transgenic animals at 2 (C) (n = 7) and 5 (D) (n = 4) months of age using (2g/kg) of Dextrose after an overnight fast. (E) Insulin tolerance test (ITT) after 6h fasting period (n = 4). (F) Serum insulin levels in 6h fasted animals (n = 4). Data are from males animals and presented as mean ± SEM. * p ≤ 0.05, ** p ≤ 0.005.
