Figure 6
From: Attenuation of Streptococcus suis virulence by the alteration of bacterial surface architecture
Resistance to whole blood killing and adherence and invasion ability to Hep-2 and HUVEC.
(A) Resistance analyses of S. suis strains to human whole blood killing. Following 8 hours of incubation of bacteria (05ZYH33, ΔneuB or Δcps2B at the concentration of 106 CFU/ml) with human whole blood, their survival levels were determined by plating. Data shown here are expressed in means ± SD. The asterisk indicated that the survival number of the mutants was significantly lower than that of the wild-type strain, at a P value of <0.05. (B) Enhanced adherence capability of the mutants (ΔneuB or Δcps2B) to Hep-2 and HUVEC cells. Data shown here are means ± SD of intracellular bacteria/ml. The asterisk indicates that the adherence values of the mutants was significantly higher than that of the wild-type strain, at a P value of <0.05. (C) Increased invasion ability of the mutants (ΔneuB or Δcps2B) to Hep-2 and HUVEC. Data shown here are means ± SD of intracellular bacteria/ml. The asterisk indicates that the invasion values of the mutants was significantly higher than that of the wild-type strain, at a P value of <0.05.
