Table 1 Stable CS knockdown accelerates tumor cell growth in vivo

From: Loss of the respiratory enzyme citrate synthase directly links the Warburg effect to tumor malignancy

Cell line

Number of mice

Day for first measuring tumor size

Tumor size at 20 days (mm3)

Mock

6

ND

0

HeLa-vector-1

6

ND

0

HeLa-vector-2

6

ND

0

HeLa-shCS1-1

12

8 (4/12), 11 (7/8), 14 (1/1)

2340.6 ± 752.1

HeLa-shCS1-3

12

8 (1/12), 11 (7/11), 14 (4/4)

2114.7 ± 806.9

HeLa-shCS1-4

12

8 (8/12), 11 (2/4), 14 (2/2)

1781.4 ± 457.6

HeLa-shCS1-6

12

8 (7/12), 11 (4/5), 14 (1/1)

1584.2 ± 511.2

  1. ND: no detectable tumor growth within 8 weeks after inoculation.
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