Figure 3

z-statistics of differential non-local network entropy (x-axis) for the six different tissues (y-axis).

The network entropy considered here is the measure (equation 2) which is defined for a stochastic diffusion matrix for maximum path lengths of order 2 (Methods). Positive z-statistics means higher entropy in cancer compared to normal. Green lines indicate the 95% confidence interval envelope and given P-values are from a normal null distribution centred at zero.