Table 2 Summary of performance parameters for the three predictive models a

From: Discovery and verification of panels of T-lymphocyte proteins as biomarkers of Parkinson's disease

 

20-spot model

14-spot model

9-spot model

Cutoff

0.67

−0.31

−2.90

Sensitivity (%)

87

100

100

Specificity (%)

81

94

88

ROC AUC

0.906

0.996

0.992

p value

< 10−8

< 10−8

< 10−8

  1. aCutoff values are expressed in terms of the likelihood PD score obtained as a linear combination of selected spot relative volumes; ROC = receiver operating characteristic; AUC = area under curve; p values refer to Wilcoxon test on PD scores. Sensitivity, specificity and ROC AUC were obtained by leave-one-out cross-validation.
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