Figure 2 | Scientific Reports

Figure 2

From: Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytes

Figure 2

Combination of SCX overexpression with mechanical stress enhanced tendon maturation in vitro.

(a) Histology of the engineered tendons after 1 week of mechanical stimulus. Scale bar, 50 um. (b) Histological score of engineered tendon. (c) Quantitative analysis of collagen fiber diameters of engineered tendons at 3 to 21 days (N = 2 to 5 each group) (d) Ultrastructure and histogram of collagen fiber diameters of engineered tendons at 3 days. SCX and mechanical interaction, *p<0.05; mechanical stress effects #, p<0.05, ##, p<0.01.

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