Figure 5
From: Digit patterning during limb development as a result of the BMP-receptor interaction
Parameter dependency of patterning.
(A) Local stability analysis. Each parameter as perturbed independently from the reference value given in Table 1 as indicated on the vertical axis and the range was recorded for which pattern were qualitatively preserved on a static domain. The numbers above and below the bar indicate how many digits were either gained (+) or lost (−) as the range was exceeded. (B) The parameter space for which the pattern is preserved is larger (black line) if parameters are changed together as illustrated for the FGF production and degradation rates. The simulations were analyzed at τ = 750. Please note that the FGF degradation rate determines the time scale of the simulations (T = 1/dF). Compensation with the FGF production rate thus allow us to simulate the processes on different time scales.
