Table 1 Values of the dimensionless parameters
From: Digit patterning during limb development as a result of the BMP-receptor interaction
Parameter | Non-dim value | Description |
|---|---|---|
Production Rates | ||
ρF | 243.1 | max production rate of F |
ρR | 0.0145 | Constant production rate of R |
ν | 1.361 | max C-dependent rate of R production |
| 12 · ρR | max F-dependent rate of B production |
ρB1 | 0.063 | Constant production rate of B in the “handplate” |
ρB2 | 3 · ρB1 | Constant production rate of B in the lower stalk (H1) |
Diffusion Coefficients | ||
D B | 2.7 | BMP diffusion constant |
D R | 0.01 · DB | Receptor diffusion constant |
Decay constants | ||
δR | 0.135 | Receptor decay constant |
δB | 0.15 · δr | BMP decay constant |
δC | ν/3 | Receptor-ligand complex decay constant |
Regulation | ||
n | 2 | Hill coefficient |
κ1 | 0.06588 | Hill constant for BMP → FGF positive feedback |
κ2 | very large | Hill constant for BMP ” FGF negative feedback |
Domain Size | ||
R Ref | 7.74 | Reference radius |
