Figure 6
Expression of furin in MDA-MB-468 cells before and after incubation with 1 and electron microscopy images of the cells after 8 h incubation with 1.
Western blot analysis (a) and quantification (b) of furin expression levels in MDA-MB-468 cells before and after incubation with 1 at 100 μM for 8 h. Expression of furin in cells treated with 1 has an obvious decrease (41.7% of GAPDH), compared with that in cells untreated (93.9% of GAPDH, 2.3-fold, p = 0.001). Low (c) and high (d) magnification Electron microscopic images of MDA-MB-468 cells after incubation with 1 at 100 μM for 8 h. Large area of clustered Gd-NPs of 1 were found at/near Golgi bodies. Scale bar in c: 2 μm. Scale bar in d: 400 nm.
