Figure 5
From: Increased NR2A:NR2B ratio compresses long-term depression range and constrains long-term memory
Impaired performance in spatial Plus Maze.
(A) Experimental set up of the water plus maze. The dotted circle in the east arm indicates the location of the fixed hidden platform. The starting position for each of the trials was the north, west or south arm. (B) In the hidden platform paradigm the wild-type were able to find the platform significantly faster than the Tg-NR2A animals on days 3–6. (C) During the transfer tests on day 7 the tg-NR2A animals spent significantly less time in the target arm than the wild-type animals (wt: 12.04 ± 1.67s, NR2A: 39.78 ± 5.5 s).
