Table 1 Number of Epistatic interactions. Number of epistatic interactions across the seven WTCCC phenotypes for different levels of filtering of the SNP pairs. The column "All" contains the number of associations that were significant after Bonferroni correction. The column "Well separated" contains the number of associations after further filtering out the interactions that were not well separated (see Methods). The column "Weak marginal(s)" contains the number of associations after further excluding SNP pairs that would have been identified by a two-stage marginal-filtering approach

From: An Exhaustive Epistatic SNP Association Analysis on Expanded Wellcome Trust Data

Phenotype

All

Well separated

Weak marginal(s)

BD

6

1

1

CD

0

0

0

CAD

56

42

42

HT

5

1

1

RA

71

4

4

T1D

2181

656

15

T2D

4

3

3

Total

2323

707

66