Figure 4

Pro-apoptotic protein marker expression following Tnv-6 treatment.

Representative Western blot gel images reveal the absence of cleaved caspase-3 (a) and PARP-1 (b) in CLL cells cultured with Tnv-6 (Tnv-6), similar to untreated cultures (Control). In contrast, cleaved forms of both proteins were detected in CLL cells cultured with fludarabine (+).