Table 1 Quantitation of MMA, ADMA and SDMA in wild-type and PRMT1 knockout MEF protein hydrolysates. The number of residues of methylated arginine derivatives per 1000 residues of arginine is shown
From: Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs
| Â | Â | PRMT1 WT | PRMT1 KO | Â |
|---|---|---|---|---|
Residue analyzed | Experiment # | Residues per 1000 arginine residues | Average fold change (KO to WT) | |
MMA | Experiment 1 | 0.16 | 0.83 | 4.73 |
| Â | Experiment 2 | 0.07 | 0.30 | Â |
ADMA | Experiment 1 | 4.36 | 3.14 | 0.52 |
| Â | Experiment 2 | 3.69 | 1.76 | Â |
| Â | Experiment 3 | 3.98 | 1.49 | Â |
SDMA | Experiment 1 | 0.34 | 0.94 | 2.76 |
