Figure 7
From: Intraovarian transplantation of primordial follicles fails to rescue chemotherapy injured ovaries
RT-PCR analysis of autophagy-specific gene expression in the ovaries of B/C-treated female mice from post-treatment week 0 to week 5th.
The expression of autophagy-specific genes is significantly reduced in a time-dependent manner after B/C treatment. Each value is the mean ± D. Ovarian ATG4a (a), ATG4b (b), ATG5 (c), ATG6 (d), LC3 (e) and GABARAP (f) expression at different follicle stages. Data are normalized to Gapdh expression and presented as the mean relative quantity compared to control. Error bars represent standard error of the mean (SEM), in a to e groups marked with different letters are significantly different from each other at p < 0.05. In a to f groups marked with similar letters are not significantly different from each other. Time points (weeks) after B/C treatment is indicated at the bottom.
