Figure 5
From: A choline derivate-modified nanoprobe for glioma diagnosis using MRI
Dynamic MRI and quantification of the signal enhancement in glioma-bearing nude mice pre-contrast and at various time points after i.v. injection of different probes.
(a) Nude mice bearing small-volume glioma were administered DTPA-Gd (top row), DP-DTPA-Gd (second row) or DPC-DTPA-Gd (third row). (b) Nude mice bearing large-volume glioma were administered DTPA-Gd (top row), DP-DTPA-Gd (second row) or DPC-DTPA-Gd (third row). (c), (d) Quantitative analysis results for the MR images. The average MR signal intensity was measured for each tumor and the relative signal enhancement was then calculated as the quotient of the intensity at various time points for the pre- and post-contrast images.
