Figure 1
From: Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest
Initial and residual γ-H2AX foci were observed in charged particle irradiated fibroblasts.
(a) γ-H2AX foci (green) were imaged at 1 and 26 h after irradiation with antiprotons (top), carbon ions, protons or 225 kVp X-rays. (b) ‘Cut-view’ images taken from compiled Z-stack images through irradiated cells show stacks of foci along antiproton paths in SOBP irradiated cells that were fixed 1 h after irradiation. (c) Restoration deconvolution was applied to images of cell nuclei from antiproton-irradiated fibroblasts. Antiproton SOBP irradiated nuclei (top) contained large clustered foci that were smaller and less frequent in antiproton plateau irradiated fibroblasts (bottom).
