Table 1 Description of experimental radiation sources used and spread out Bragg peaks employed for antiproton, proton and carbon ion beams and linear quadratic fitting parameters and RBE for each survival curve
From: Antiproton induced DNA damage: proton like in flight, carbon-ion like near rest
Incident energy | Range in water (mm) | SOBP mid-point ± half SOBP depth (mm) | Sample position (depth in water (mm)) | Dose av. LET (keV/μm) | α ± s.e. (Gy−1) | β ± s.e. (Gy−2) | RBE (SF0.1) (± s.e.) | |
---|---|---|---|---|---|---|---|---|
X-ray * | 225 kVp | n/a | n/a | n/a | ~2 | 0.61 ± 0.1 | 0.02 ± 0.05 | 1 |
X-ray ** | 225 kVp | n/a | n/a | n/a | ~2 | 0.36 ± 0.035 | 0.054 ± 0.005 | 1 |
Proton | 62 MeV | 29.1 | 18.6 ± 10.2 | 2 | ~2 | 0.57 ± 0.06 | 0.047 ± 0.01 | 1.22 ± 0.07 |
Proton | 62 MeV | 29.1 | 18.6 ± 10.2 | 18 | ~6 | 0.53 ± 0.05 | 0.035 ± 0.009 | 1.2 ± 0.06 |
Carbon ion | 62 MeV/u | 10.8 | 6.8 ± 0.7 | 3 | ~70 | 0.96 ± 0.08 | 0.094 ± 0.03 | 2.03 ± 0.06 |
Carbon ion | 62 MeV/u | 10.8 | 6.8 ± 0.7 | 6.8 | ~150 | 2.04 ± 0.092 | 0 | 3.88 ± 0.05 |
Antiproton | 126 MeV | 116.2 | 100 ± 5 | 23 | ~4 | 0.63 ± 0.03 | 0 | 0.94 ± 0.17 |
Antiproton | 126 MeV | 116.2 | 100 ± 5 | 100 | ~19 | 1.05 ± 0.07 | 0 | 1.48 ± 0.17 |