Figure 3
From: InterMOD: integrated data and tools for the unification of model organism research
The utility of cross-species analysis.
Illustration of the principle of a cross-species analysis report page using a set of rat genes linked with motor neuron degeneration, Gsn, Ppid and Brd2 and further expression, disease and phenotype data extracted from other MOD InterMine databases based on their respective orthologs. Data are drawn from mouse, human and zebrafish, to enhance the information known about the rat gene list: (1) The gene ontology enrichment can be compared and contrasted across species; (2) A tissue specific gene expression dataset is not available in the rat database, so data from mouse are used instead, to complement the analysis; (3) Data from zebrafish provide further evidence for a motor neuron degeneration phenotype and for cross-species conservation of gene function related to this phenotype; (4) A disease ontology comparison tool provides a direct link to human disease and data.
