Figure 1
From: S-nitrosylation of ERK inhibits ERK phosphorylation and induces apoptosis
Elevated NO levels induce apoptosis in MCF-7 cells.
(A–B) SNP induces significantly elevated apoptosis and HB reverses the effect. (C) SNP accelerates the process of procaspase-9 and PARP-1. (D–E). Quantification of cell outer NO levels using Griess method and intracellular NO levels using DAF fluorescence staining.
