Figure 5
From: Intravital analysis of vascular permeability in mice using two-photon microscopy
Hyper-permeability occurs in postcapillary venules.
(A) Microvasculature in the ear skin. Arteriole (red), capillaries (green) and post capillary venules (blue) are shown. (B) Sequential images after histamine injection. Elapsed time is shown in the bottom left of each image. Red arrows indicate initiation sites of leakage from postcapillary venules. Some areas of postcapillary venules became undetectable thereafter (yellow arrowheads). (C) Kinetics of the MFI in the area of arterioles (red), capillaries (green) and post capillary venules (blue) after histamine injection. Arrow denotes the timepoint of histamine injection.
