Figure 2 | Scientific Reports

Figure 2

From: Antioxidant enzyme, 3-mercaptopyruvate sulfurtransferase-knockout mice exhibit increased anxiety-like behaviors: a model for human mercaptolactate-cysteine disulfiduria

Figure 2

Homozygous (null) MST-knockout mice.

(a) PCR genotyping of offspring produced from mating between MST-KO mice. Genomic DNA was obtained from #44-T-7-3-4-2-8 to 11 (male homozygous) (lanes 1 to 4 in the above order). (b) Western blot analysis for a MST-KO mouse (#44-T-3-2) with overreaction. MM, molecular marker; arrow, rhodanese (the MST antibody slightly cross-reacted with rhodanese); Cont, control mice; KO, MST-KO mice. (c) Microscopic examination (HE staining) of a MST-KO (#44-T-3-2). Bars, 200 μm. (d) Nissl staining for coronal sections of the hippocampal areas of wild-type and the mutant adult brains (#44-H-3-2-1 to 3 and #44-H-3-3-9 to 12). Cont, control mice; KO, MST-KO mice. Bars, 200 μm.

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