Figure 2
From: Common dysfunctional variants in ABCG2 are a major cause of early-onset gout
Odds ratios for ABCG2 dysfunctions among gout patients in each onset age group.
Shown are the odds ratios (ORs) on a log10 scale of the gout risks for each onset age group and ABCG2 dysfunction. ORs and 95% confidence intervals (CIs) for each ABCG2 dysfunction were obtained by comparing with full function and adjusted for body mass index with logistic regression analysis. Circles and diamonds with horizontal lines indicate ORs with 95% CIs of each onset age groups. All ABCG2 dysfunction levels significantly increased the risk of gout (OR > 2.38) in all onset-age groups. Severe ABCG2 dysfunction especially increased the risk of early-onset gout, conferring an adjusted OR of 22.2.
