Figure 6
Concentration polarization of ox-LDL induces ROS generation as well as expression of NADPH oxidase subunits p22phox and p47phox, p-p38 and p-NF-κB.
(A) There is greater increase of ROS generation in the permeable than in the non-permeable group measured by flow cytometry. (B) to (E) Increased expression of NADPH oxidase subunits p22phox and p47phox, p-p38 MAPK and p-NF-κB, significantly more in the permeable than in the non-permeable group. The samples were derived from the same experiment and gels/blots were processed in parallel. Bar graphs represent data in mean ± SD based on 5 experiments, * P < 0.05 vs. non-permeable group.
