Figure 6
From: Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks
Different states of insulin resistant pathway under two contrast conditions in three tissues.
From left to right, the subnetworks correspond to adipose, muscle and liver respectively. The subnetworks in the top level correspond to normal condition (WKY) and the subnetworks in disease condition (GK) are listed at the bottom level. Genes from WKY tissues are colored in white, while in green/red according to down/up-regulated sitations in GK. Given one tissue, all the differential interactions in IR pathway are casted to normal or disease strain. A green edge means that the corresponding two genes are strongly and negatively correlated, while red one indicates strongly positive correlation. The gray edges mean that though they are not differential interactions, but their two nodes (genes) are simultaneously differentially expressed.
