Figure 2
RSG-induced PKM2 protein and mRNA up-regulation is STAT6-dependent.
(a) Western blot and (b) real-time PCR analysis of PKM2 expressions in livers of control and RSG-treated mice, (n = 5/group). Graphs represent mean ± S.E.M expressed as arbitrary units normalized to the mean of control WT mice. # = p ≤ 0.05, ** = p ≤ 0.01, ### = p ≤ 0.001 (* WT vs. STAT6-deficient mice; #Control vs. RSG-treated mice) determined by one way analysis of variance (ANOVA) test. (PKM2 protein Student's t-test p = 0.003, control WT vs. STAT6-deficient mice). All runs were done in parallel with the same experimental conditions.
