Figure 5
Enhanced RSG-induced adipogenesis in STAT6-deficient mice.
(a) Epididymal (WATe) and intra-abdominal (WATi) white adipose tissue weights of control and RSG-treated mice expressed as percentage of total body weight, (n = 5–8/group). (b) Representative hematoxylin-eosin stained images of WATe derived from WT and STAT6-deficient mice (upper panels) and their computer-assisted transformation (lower panels). Adipocytes are colored according to their size. (c) Histogram of adipocyte size distribution and the bar graph of adipocyte diameter of control and RSG-treated mice. Data were obtained from 6 images/mouse derived from two sections of three different levels, n = 5 mice/group. (d) Serum leptin levels measured by ELISA analysis (n = 4–5/group). Graph represents mean ± S.E.M; ** = p ≤ 0.01, *** ### = p ≤ 0.001 (* WT vs. STAT6-deficient mice; #Control vs. RSG-treated mice) determined by one-way analysis of variance (ANOVA) test.
