Table 1 Demographic, clinical and lab data of patients diagnosed with PCR, serology and culture as bacterial meningitis or aseptic meningitis/encephalitis

From: Aetiologies of Central Nervous System infections in adults in Kathmandu, Nepal: A prospective hospital-based study

 

Total enrollees

Enteroviruses

JEV

N.meningitidis

S.pneumoniae*

HSVΦ

S.aureus#

Dual infections

 

N = 87

N = 9

N = 7

N = 5

N = 3

N = 2

N = 1

N = 5

Age

30(22–54)

39(33–53)

42(27–67)

24(20–30)

22(22–45)

21(35)

27

24(22–27)

Male

50(57)

5(55)

4(57)

4(80)

2(66)

1(50)

1

3(60)

Median duration of illness

7(8–14)

7(6–14)

7(4–7.5)

2(1.5–2)

9(1–30)

7(90)

45

10(3–30)

No previous treatment/referral

39(44)

5(55)

2(28)

4(80)

2(66)

1(50)

1

1(20)

Clinical Features

        

Fever

77(89)

8(88)

7(100)

5(100)

3(100)

2(100)

2

5(100)

Headache

56(64)

5(55)

5(71)

4(80)

1(33)

1(50)

2

5(100)

Vomiting

52(60)

5(55)

5(71)

5(100)

1(33)

1(50)

1

3(60)

Alteration of consciousness

37(42)

4(44)

4(57)

1(20)

1(33)

1(50)

0

2(40)

Seizure

16(18)

1(11)

1(14)

1(20)

1(33)

0

0

1(20)

Neck stiffness

48(55)

5(55)

3(42)

4(100)

3(100)

1(50)

1

4(80)

GCS<15

35(40)

4(44)

3(42)

1(20)

1(33)

0

0

1(20)

Travel

10(11)

1(11)

1(14)

2(40)

0

0

0

0

CSF

        

Glucose(g/dl)

53(31–67.5)

53(37–56)

79(47.5–95.5)

18(5–38)

12(10–26)

55(43)

70

42(29–58)

Protein(g/dl)

90(30–185.5)

78(29–218)

144(135–162)

300(266–330)

330(168–354)

54(137)

39

82(48–152)

WBC(10e6/ml)

22(5.5–167.5)

25(2–64)

42(25.5–111.5)

630(480–1500)

140(109–1120)

30(18)

3

180(140–1120)

Neutrophils (%)

10(1–40)

15(1–20)

10(7–25)

85(80–90)

84(10–96)

70(5)

1

47(25–70)

Lymphocytes (%)

12(3–70)

72(1–80)

70(30–85)

10(10–15)

16(4–90)

30(95)

2

53(30–75)

Hematology

        

TLC(10e6/ml)

10.7(8.3–14.65)

6.7(6.5–10.1)

9.1(8.75–14)

15(10.7–21.1)

8.7(18.1–27.1)

13.2(5)

5.8

10.3(10.1–14.9)

Neutrophils (%)

80(70–89.5)

85(66–90)

86 (73–89)

95(89–97)

86(84–95)

70(40)

63

90(80–92)

Lymphocytes (%)

19.5(10–29)

15(10–30)

14(11–27)

5(3–11)

14(5–16)

28(55)

34

8(7–16)

  1. 1Values represent number (percentage) in categorical data and median (Inter-quartile range; IQR) in continuous data in total enrollees, JEV, enteroviruses, N. meningitidis and dual infections.
  2. 2*Data for S. pneumoniae -values represent median (percentage) in categorical data and median (range) in continuous data.
  3. 3ΦData for 2 patients with HSV infection are tabulated with one in the bracket ( ). Categorical data are presented as number (percentage) and individual patient data is tabulated for both patients [with one in bracket ( )] in categorical variables.
  4. 4#Individual patient's data is tabulated for S. aureus.
  5. 5Dual infections (n = 5) = bacterial + viral (n = 4); viral + viral (n = 1).
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