Figure 3 | Scientific Reports

Figure 3

From: Long-term biopersistence of tangled oxidized carbon nanotubes inside and outside macrophages in rat subcutaneous tissue

Figure 3

Histological and HRTEM images of t-ox-MWCNTs in the tissue at 2 years after implantation.

(a) Optical micrograph and (b to d) HRTEM images. Macrophages (MΦ), fibroblasts, multinucleated foreign body giant cells (FBGC) and capillaries were observed in the granulation tissue. The thin fibrous connective tissue was well organized (Fig. 3a and b). Many mitochondria and primary lysosomes (white arrows in Fig. 3c) were observed in the macrophage as the cytoplasmic process of the macrophage invaginated. ICP, invaginating cytoplasmic process. The histological and HRTEM images are representative of greater than 100 independent observations areas in each implanted t-ox-MWCNT.

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