Figure 7

Electron diffractions of t-ox-MWCNTs in the tissue at 2 years after implantation.
(a) HRTEM image of t-ox-MWCNTs in the secondary lysosome inside a macrophage. (b) High-magnification HRTEM image of the boxed area shown in panel (a) and the electron diffraction pattern (inset) of the aggregated t-ox-MWCNTs (indicated by a white dashed circle). (c) HRTEM image of t-ox-MWCNTs in the intercellular space. (d) High-magnification TEM image of the boxed area shown in panel (c) and the electron diffraction pattern (inset) of aggregated t-ox-MWCNTs. (e) HRTEM image of t-ox-MWCNTs in the secondary lysosome inside a second macrophage. (f) High-magnification TEM image of the boxed area in panel (e) and the electron diffraction pattern (inset) of aggregated t-ox-MWCNTs. Nu, nucleus. The HRTEM images are representative of greater than 100 independent observation areas in each implanted t-ox-MWCNT.