Figure 3
From: Transient and selective suppression of neural activity with infrared light
Infrared inhibition of electrically-evoked muscle contraction.
(a) A suction electrode stimulated muscle contractions in the I1/I3 muscles as measured by a force transducer. A 200 μm diameter optical fiber positioned distal (~1 cm) to the electrical stimulus inhibited AP propagation of some motor units. (b) Electrically-evoked force in response to 2-sec stimuli (τpe = 1 ms; 0.7 mA; 10 Hz) separated by a 12-second interval. (c) A 3-sec infrared pulse train (λ = 1450 nm; τpo = 0.2 ms; 0.54 J/cm2; indicated by horizontal red bar) at 200 Hz delivered in conjunction with the third electrical stimulus inhibited force generation. (d) Average I1/I3 contraction force in response to electrical stimulation with and without the infrared pulse train (*** p < 0.001; without laser, N = 2 nerves, n = 10 trials; with laser, N = 2 nerves, n = 10 trials). Data are presented as mean ± SEM.
