Figure 1 | Scientific Reports

Figure 1

From: Interplay of cytoskeletal activity and lipid phase stability in dynamic protein recruitment and clustering

Figure 1

Schematic representation of the simulation model.

The membrane is portrayed as a surface where the relative concentration of lipids ϕ(r,t) is plotted as a grey scale; areas enriched in raft-like lipids are represented as darkened regions. Cytoskeleton-anchored proteins (X) are represented by red inclusions that nucleate lipid rafts. These proteins can eventually detach after an average time τ due to the active re-polymerization of the actin meshwork. Raftophilic proteins (P) diffuse and are attracted to lipid rafts, causing transient aggregation of these proteins in areas enriched with raft-like lipids, forming protein clusters.

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