Figure 3 | Scientific Reports

Figure 3

From: Distinguishing between genotoxic and non-genotoxic hepatocarcinogens by gene expression profiling and bioinformatic pathway analysis

Figure 3

DEG (differentially expressed gene) heat map and hierarchical clustering results distinguishing GTX from NGTX compounds.

These data are from the training set of three GTX (G; 2-AAF, DEN, MeDAB), three NGTX (N; clofibrate, dioxane, DL-ethionine) carcinogens and the test set of four unknown carcinogens (T; DCP, methyleugenol, sodium nitrite, urethane). The expression patterns for the DEGs selected from the overall heat map on the left side are shown in color. The red color represents high expression and the blue color low expression, within the −2.9~2.9 (Figure 3A) and −3.5~3.5 (Figure 3B) ranges, respectively. The magnified section on the right shows parts of DEG lists and hierarchical clustering results of the upper part. (a): single-treatment results, (b): multiple-treatment results.

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