Figure 4 | Scientific Reports

Figure 4

From: Controlling Cellular Uptake of Nanoparticles with pH-Sensitive Polymers

Figure 4

Phase diagrams describing the equilibrium state of the particle-membrane systems.

(a) the receptor-ligand interaction strength verse the ionized degree N, where rcut = 1.0 nm and σP = 2.5 e/nm2; (b) the receptor-ligand interaction range verse the ionized degree N, where and σP = 2.5 e/nm2; (c) the surface charge density verse the ionized degree N, where rcut = 1.0 nm and . In (a)–(c), the membrane is neutrally charged. (d) Negative lipid fraction (i.e., the number of negative lipids/the total number of lipids and receptors) verse the ionized degree N, where , σP = 2.5 e/nm2 and rcut = 1.0 nm.

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