Figure 3
From: Metabolic Characterization of a Sirt5 deficient mouse model
Metabolite and transcription analysis of chow-fed Sirt5−/− mice after sacrifice.
The 12-week-old wt and knockout male mice were fasted for 24 hours and sacrificed. N = 4–6. (a). AST, ALT, Triglycerides (Trig), NEFA, cholesterol, HDL-cholesterol and LDL-cholesterol in plasma. (b) and (c). The expression profile of a selected set of metabolic genes in the liver and gastrocnemius muscle. mRNA level of each gene was normalized to the housekeeping gene 36B4 and further normalized to the expression level in Sirt5+/+ mice. ** P < 0.01.
