Figure 6

VSL#3 alters the phylum-level distribution of the (a) luminal/stool and (b) mucosally-adherent microbiota.
Pie charts depict median standardized abundance (% of total) of the indicated phyla. (a) Standardized abundances of taxa contributing > 1% were log-transformed, pairwise comparisons were made using Student t test and P-values were FDR corrected for multiple testing using the Benjamini and Hochberg procedure. SPF = 5 mice, SPF + VSL#3 = 4 mice. (b) Luminal/stool standardized log-transformed abundances were compared using a one way ANOVA by fitting a linear mixed model as described in Materials and Methods and P-values were corrected for multiple testing as in (a). SPF = 10 mice in 4 cages, SPF + VSL#3 = 14 mice in 5 cages.