Table 1 Various combinations of Kdm4A and Kdm4B mutations and associated adult phenotypes
From: Drosophila Kdm4 demethylases in histone H3 lysine 9 demethylation and ecdysteroid signaling
Abbreviation | Genotype | Adult Phenotype |
|---|---|---|
Kdm4A +/− | Kdm4AKG04636/CyO | Viable, fertile, grossly normal morphology |
Kdm4B +/− | Kdm4BEY10737/CyO | Viable, fertile, grossly normal morphology |
Kdm4A +/− , Kdm4B +/− | Kdm4AKG04636, Kdm4BEY10737/CyO | Viable, fertile, grossly normal morphology |
Kdm4A −/− , Kdm4B +/− | Kdm4AKG04636, Kdm4BEY10737/Kdm4AKG04636,+ | Viable, fertile, grossly normal morphology |
Kdm4A +/− , Kdm4B −/− | Kdm4AKG04636, Kdm4BEY10737/+, Kdm4BEY10737 | Viable, fertile, grossly normal morphology |
Kdm4A −/− , Kdm4B −/− | Kdm4AKG04636, Kdm4BEY10737/Kdm4AKG04636, Kdm4BEY10737 | No viable adults recovered |
