Table 1 Morphometric and electrophysiological studies of endplates of the patient

From: HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA

 

Patient

Controls

AChR index

0.87 ± 0.01 (27)

3.01 ± 0.11 (85)

EPP quantal contenta

27 ± 8 (18)

31 ± 1

MEPP amplitude (mV)b

0.23 ± 0.015 (16)

1.00 ± 0.025 (165)

  1. Values represent mean ± standard error (SE). Numbers in parenthesis indicate number of endplates (EPs).
  2. aQuantal content of EP potential (EPP) at 1 Hz stimulation corrected for resting membrane potential of −80 mV, nonlinear summation and non-Poisson release.
  3. bThe amplitude of the miniature EP potential (MEPPs) are corrected for resting membrane potential of −80 mV and a mean muscle fiber diameter of 5 μm. Temperature was 29 ± 0.5°C for EPP and MEPP recordings.
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