Table 1 Samples with JAK1 mutations in the TCC project+

From: JAK1 truncating mutations in gynecologic cancer define new role of cancer-associated protein tyrosine kinase aberrations

 

Case

Tissue

Total

Non-synonymous Mutation#

Truncating Mutation#

Brain

79

1

0

Breast

427

10

1

Colorectal*

539

23

9

Esophagus

44

2

0

Gallbladder

2

1

0

GYN**

635

53

36

(Corpus uterine***)

(348)

(43)

(33)

HEME-CLL

94

2

0

Kidney

243

8

0

Lung

603

14

2

Pancreas

161

4

1

Prostate

52

1

0

Skin

209

10

1

Soft tissue

45

2

0

Stomach

55

4

2

  1. +See supplementary Table 1 for the complete list.
  2. *Large bowel, small intestine, and rectum-anus.
  3. **Cervix, endometrial, gynecologic, ovary, uterus, vagina, and vulva.
  4. ***Endometrium and uterus.
  5. #Some cases have more than one mutations, for examples, 14 cases of GYN tumors have two different JAK1 truncating mutations and thus the total JAK1 truncating mutation events detected in GYN cancer is 50.
Back to article page