Table 2 JAK1 frame-shift truncating mutation in TCC tumors and matched normal tissues+
Barcode | JAK1 mutation (TCC) | Mutation allele fraction (TCC) | Primary tissue | ID | JAK1 mutation in tumor (Sanger Sequencing) | Matched normal tissue | ID | JAK1 mutation in normal tissue (Sanger Sequencing) |
|---|---|---|---|---|---|---|---|---|
DS-58859 | K860fs | 0.85 | Endometrium | 1T | mut | N/A | N/A | N/A |
DS-57828 | K860fs | 0.53 | Endometrium | 2T | mut | Endometrium | 2N | wt |
DS-55004 | K142fs; K860fs | 0.19; 0.60 | Uterus** | 3T | K142wt; K860mut | Uterus | 3N | wt |
DS-60386 | K860fs | 0.45 | Endometrium* | 4T | mut | Large Bowel | 4N | wt |
DS-55027 | R174X | 0.42 | Uterus** | 5T | mut | Uterus | 5N | wt |
DS-55352 | P430fs | 0.31 | Uterus** | 6T | mut | Uterus | 6N | wt |
DS-80370 | K142fs; P430fs | 0.37; 0.26 | Endometrium | 7T | K142mut; P430mut | Endometrium | 7N | wt |
