Figure 4

Assessment of oxidative stress (A) and antioxidative capacity (B).

Changes in general reactive oxygen species (ROS) levels and malondialdehyde (MDA) generation, a final degradation product of lipid peroxidation, are shown in (A) and superoxide dismutase (SOD) and reduced glutathione (GSH) in (B). : P < 0.01 compared with normal control group, : P < 0.01 compared with H-R group (cell injury induced by hypoxia reoxygenation group). H-R PHB^–: transduced with lentivirus carrying siRNA PHB; H-R PHB⁺: transduced with lentivirus carrying Phb; H-R negative control: transduced with control viruses. AOX: antioxidant.