Figure 2
From: Targeting microRNA-23a to inhibit glioma cell invasion via HOXD10
HOXD10 is a direct target gene of miR-23a.
(A). Data of TargetScan showed the putative target sequence of miR-23a in the 3′-UTR of HOXD10. (B). Luciferase report assay data showed that co-transfection of U251 and U87 cells with miR-23a and wild type HOXD10 3′-UTR led to a remarkable decrease in luciferase activity. However, co-transfection with miR-23a and mutant HOXD10 3′-UTR had no effect on luciferase activity and co-transfection with negative control (NC) miRNA and wild type HOXD10 3′-UTR or mutant HOXD10 3′-UTR also showed no difference. Control: U251 and U87 cells co-transfected with blank vector and wild type HOXD10 3′-UTR or mutant HOXD10 3′-UTR. ** means P<0.01 vs. Control.
